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ISSN 1998-9539

Synthesis of Nanosized Monocationic β-Cyclodextrin Conjugates Containing Residues of Pharmacologically Important Acids

Dmitry A. Shipilov,a@ Galina I. Kurochkina,a Aleksander A. Sergievich,b and Mikhail K. Gracheva
aMoscow State University of Education, 129164 Moscow, Russia
bFar Eastern Federal University, 690091 Vladivostok, Russia
@Corresponding author E-mail:
DOI: 10.6060/mhc170510s
Macroheterocycles2017 10(2) 238-242

New nanosized cationic β-cyclodextrins conjugates containing residues of pharmacologically important monocarbonic aromatic acids at the primary hydroxyl groups were synthesized with the use of benzoic, p-aminobenzoic, nicotinic and i-nicotinic acids. The position of substituents in carbohydrate fragments of CDs was unambiguously determined by 1H and 13C NMR spectroscopy. During the investigation, some features of the regiodirected synthesis of such nanosized cationic β-cyclodextrins conjugates were revealed.


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