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ISSN 1998-9539

Novel Podands Containing N-Arylthiosemicarbazide Moiety

Le Tuan Anh,a@ Dao Thi Nhung,a Le Anh Tuyet,a Tran Thi Thanh Van,a Truong Hong Hieu,b,c Nguyen Van Tuyen,c,d Nguyen Thi Thanh Phuong,a Anatoly T. Soldatenkov,e Vasily E. Kotsuba,e and Dang Thi Tuyet Anhc,d
aUniversity of Science, Vietnam National University, Hanoi, Vietnam
bDepartment of Biotechnology, Vietnam-Russia Tropical Centre, Hanoi, Vietnam
cInstitute of Chemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam
dGraduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam
ePeoples’ Friendship University of Russia, 117198 Moscow, Russia
@Corresponding author E-mail:
DOI: 10.6060/mhc170289l
Macroheterocycles 2017 10(2) 243-246


Six novel biological active podands based on N-arylthiosemicarbazide were synthesized from 1,5-bis(2-formylphenoxy)-3-oxapentane or 1,8-bis-(2-formylphenoxy)-3,6-dioxaoctane. All podands have tested cytotoxicity on human cancer cell lines RL, MCF7, RD, and HepG2 and antimicrobial activity.


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