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ISSN 1998-9539

Synthesis of 4-Nitro- and 4-Aminophenylazacrown Ethers

Aleksandr S. Oshchepkov,a,c Maksim S. Oshchepkov,b,c Alexander V. Anisimov,a and Olga A. Fedorovaa,b,c@
аChemistry Department, M.V. Lomonosov Moscow State University, 119992 Moscow, Russia
bD.I. Mendeleev University of Chemical Technology of Russia,125047 Moscow, Russia
cA.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 119991 Moscow, Russia 
@Corresponding E-mail:
The study is dedicated to finding optimal reaction conditions for the introduction of 4-nitro- and 4-aminophenyl substituents into the structure of azacrown ethers with a varied ratio of oxygen to nitrogen heteroatoms. The synthetic procedure is proposed for the synthesis of 4-nitroaryl derivatives of crown ethers. This method is remarkably simple, has easy work-up and affords the formation solely of the monoarylation product.



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