Impact Factor 2021 = 1.200 has been issued by ISI Web of Knowledge (JCR 2021).

SCImago Journal & Country Rank

ISSN 1998-9539

Diaminothiadiazoles – Building Blocks for Macroheterocycles

Elena A. Danilova, Tat’yana V. Melenchuk, Olga N. Trukhina, and Mikhail K. Islyaikin@

Ivanovo State University of Chemistry and Technology, 7, Engels Av., 153000, Ivanovo, Russia

@Corresponding author E-mail:


DOI: 10.6060/mhc2010.1.68

Macroheterocycles 2010 3(1) 68-81


Syntheses and properties of 2,5-diamino-1,3,4-thiadiazole, 3,5-diamino-1,2,4-thiadiazole and 3-N-alkyl-5-amino-2-imino-1,3,4-thiadiazolines – building blocks for macroheterocyclic compounds are discussed in this review. The convenient methods of their synthesis were elaborated and peculiarities of their geometrical structure were discussed. The mechanism of 3,5-diamino-1,2,4-thiadiazole formation from 2-imino-4-thiobiuret was simulated by quantum chemistry methods at the level of Density Functional Theory (DFT).


MHC2010_t03n01_68-81.pdf990.05 KB