Crystal Structures of trans-Diiodidobis(2-hydroxyethylamine)platinum(II) and trans-Dichloridobis(2,2’-dihydroxydiethylamine)platinum(II)

Frank W. Heinemann,^a Živadin D. Bugarčić (1954–2017),^b and Tanja V. Soldatović^c@

^aDepartment of Chemistry and Pharmacy, Friedrich-Alexander-University of Erlangen-Nürnberg, 91058 Erlangen, Germany

^bDepartment of Chemistry, Faculty of Science, University of Kragujevac,34000 Kragujevac, Serbia

^cDepartment of Chemical-Technological Sciences, State University of Novi Pazar, 36300 Novi Pazar, Serbia

^@Corresponding author E-mail: tsoldatovic@np.ac.rs

DOI: 10.6060/mhc200389s
Macroheterocycles 2020 13 (3) 210-214

The crystal structures of trans-diiodidobis(2-hydroxyethylamine)platinum(II), trans-[PtI₂(mea)₂], (1) and trans-dichloridobis(2,2’-dihydroxydiethylamine)platinum(II), trans-[PtCl₂(dea)₂], (2) were determined by single crystal X-ray diffraction experiments. Crystallization of (1) occurs in the monoclinic space group P2₁/c with a = 9.457(1)Å, b = 14.719(2) Å, c = 8.246(1) Å, Z = 4 for d_calc = 3.235 mg/m³ while crystallization of (2) occurs in the tetragonal space group P4₂/mbc, a = 9.8624(6) Å, c = 14.2998(9) Å, Z = 4 for d_calc = 2.274 mg/m³. The square-planar coordination geometry of both complexes is formed by two N atoms of the 2-hydroxyethylamine (1) or 2,2’-dihydroxydiethylamine (2) ligands in trans positions and two I^- (1) or Cl^- (2)anions. Both structures are stabilized by intra- and intermolecular hydrogen bonds.

References:

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1. Wang D., Lippard S.J. Nat. Rev. Drug. Disc. 2005, 4, 307-320.
https://doi.org/10.1038/nrd1691

2. Lippert B. Cisplatin: Chemistry and Biochemistry of a Leading Anticance Drug. Zürich: Wiley-VCH, 1999. 576 p.
https://doi.org/10.1002/9783906390420

3. Jamieson E.R., Lippard S.J. Chem. Rev. 1999, 99, 2467-2466.
https://doi.org/10.1021/cr980421n

4. Jakupec M.A., Galanski M., Keppler B.K. Rev. Physiol. Biochem. Pharmacol. 2003, 146, 1-53.
https://doi.org/10.1007/s10254-002-0001-x

5. Zimmermann W., Galanski M., Keppler B.K., Giester G. Inorg. Chim Acta 1999, 292, 127-130.
https://doi.org/10.1016/S0020-1693(99)00175-9

6. a) Wilson A.J.C. International Tables for Crystallography (Ed.) Dordrecht: Kluwer Academic Publishers, 1992, tables 6.1.1.4 (500-502), 4.2.6.8 (219-222), 4.2.4.2 (193- 199);
(b) COLLECT Bruker-Nonius 2002 for data collection;
(c) EvalCCD, Bruker-Nonius 2002 for data reduction; (d) SADABS 2.06, Bruker-AXS 2002 for absorption correction;
(e) SHELXTL NT 6.12, Bruker AXS 2002 for structure determination;
(f) SHELXL 2018/3, Sheldrick G.M. Acta Crystallogr. 2015, C71, 3-8 for refinement;
https://doi.org/10.1107/S2053229614024218
(g) SHELXTL NT 6.12, Bruker AXS 2002 for molecule projection.

7. Petrović Z.D., Djuran M.I., Heinemann F.W., Rajković S., Trifunović S.R. Bioorg. Chem. 2006, 34, 225-234.
https://doi.org/10.1016/j.bioorg.2006.06.003

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Crystal Structures of trans-Diiodidobis(2-hydroxyethylamine)platinum(II) and trans-Dichloridobis(2,2’-dihydroxydiethylamine)platinum(II)

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