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ISSN 1998-9539

2,6-Dibrominated 3,5-DistyrylBODIPYs as Photosensitizer Dyes for Photodynamic Antimicrobial Chemotherapy

Kelechi A. Lebechi, Bokolombe P. Ngoy, John Mack@ and Tebello Nyokong

Institute of Nanotechnology Innovation, Department of Chemistry, Rhodes University, 6140 Makhanda, South Africa

@Corresponding author E-mail: j.mack@ru.ac.za

 

This article was submitted to a special issue dedicated to Prof. Dieter Wöhrle’s 80th Birthday

 

A 2,6-dibrominated BODIPY core dye with a meso-pyrenyl groups has been investigated for use as a photosensitizer dye in photodynamic antimicrobial chemotherapy in the context of both gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacteria, along with a π-extended 3,5-di-4-carboxystyrylBODIPY dye. The dyes are found to be effective for the treatment of S. aureus, but not in the case of E. coli.