Журнал "Макрогетероциклы"

^aSchool of Chemistry and Chemical Engineering, Jiangsu University, 212013 Zhenjiang, P. R. China

^bDepartment of Chemistry, Rhodes University, 6140 Grahamstown, South Africa

^cState Key Laboratory of Coordination Chemistry, Nanjing University, 212013 Nanjing, P. R. China

^@1E-mail: liangxu@ujs.edu.cn

^@2E-mail: j.mack@ru.ac.za

^@3E-mail: chenqy@ujs.edu.cn

 

DOI: 10.6060/mhc181005l

Macroheterocycles 2018 11(4) 421-428

 

A series of 3,5-distyryl and meso-morpholino/hydroquinoline BODIPY dyes have been synthesized and characterized. The electronic structure was investigated by optical spectroscopy, electrochemistry and TD-DFT calculations. In addition, they fluoresce in the biological window and are hence potentially suitable for use as cellular imaging agents. The meso-1,2,3,4-isoquinoline substituted BODIPYs 3с-d interact strongly with DNA and this enhances their ability to act as bioimaging agents. In contrast, the meso-morpholine substituted BODIPYs 3a-b were found to have higher cell toxicity.