Calixarene Derivatives for (Nano)Biotechnologies

Roman Rodik, Mykola Poberezhnyk, and Vitaly Kalchenko^@

The article is devoted to 75th anniversary of Academician A. Yu. Tsivadze

Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 02660 Kyiv, Ukraine

^@Corresponding author E-mail: vik@ioch.kiev.ua

DOI: 10.6060/mhc171150k

Macroheterocycles 2017 10(4-5) 421-431

This review summarizes the author's research in the field of bio-medical application of modified calixarenes as well as their nano-associates. The paper includes results of design and investigation of the calixarenes as intracellular transport modulators of Ca and Na cations, as well as effective and selective phosphatases inhibitors. The antibacterial and anticoagulant properties of series water-soluble positively or negatively charged calixarenes are described. Also, utilization of calixarenes for hierarchical formation of nanoparticles for nanobiotechnological application (DNA transfection and bio-imaging) is discussed.

References:

Click here to expand or collapse this section

1. Calixarenes in the Nanoworld (Vicens J., Harrowfield J., Eds.), Dordrecht: Springer, 2007.

2. Calixarenes and Beyond (Neri P., Sessler J.L., Wang M.-X., Eds.), Switzerland: Springer, 2016.
https://doi.org/10.1007/978-3-319-31867-7

3. Rodik R.V., Boyko V.I., Kalchenko V.I. Front. Med. Chem. 2016, 8, 206–301.

4. Rodik R.V., Boyko V.I., Danylyuk O.B., Suwinska K., Tsymbal I.F., Slinchenko N.V., Babich L.G., Shlykov S.O., Kosterin S.O., Lipkowski J., Kalchenko V.I. Tetrahedron Lett. 2005, 46, 7459.
https://doi.org/10.1016/j.tetlet.2005.07.069

5. Labyntseva R.D., Slinchenко N.M., Veklich T.O., Rodik R.V., Cherenоk S.О., Boyko V.I., Kalchenko V.I., Коsterin S.О. Ukrainian Biochemical Journal 2007, 79, 44–54.

6. Veklich T.A., Shkrabak A.A., Slinchenko N.N., Mazur I.I., Rodik R.V., Boyko V.I., Kalchenko V.I., Kosterin S.A. Biochemistry
(Moscow) 2014, 79, 417–424.
https://doi.org/10.1134/S0006297914050058

7. Veklich T.O., Kosterin S.O., Rodik R.V., Cherenok S.O., Boyko V.I., Kalchenko V.I. Ukrainian Biochemical Journal 2006, 78, 70–86.

8. Veklich T.O., Shkrabak O.A., Kosterin S.O., Rodik R.V., Cherenok S.O., Boyko V.I., Kalchenko V.I. Ukrainian Biochemical Journal 2006, 78, 53–63.

9. Veklich T.O., Shkrabak A.A., Cherenok S.O., Kalchenko V.I., Kosterin S.O. Ukrainian Biochemical Journal 2012, 84, 49–57.

10. Klyachina M.A., Boyko V.I., Yakovenko A.V., Babich L.G., Shlykov S.G., Kosterin S.O., Khilya V.P., Kalchenko V.I. J. Inclusion Phenom. 2008, 60, 131–137.
https://doi.org/10.1007/s10847-007-9361-9

11. Bevza А.А., Labintseva R.D., Rodik R.V., Cherenok S.O., Kosterin S.O., Kalchenko V.I. Ukrainian Biochemical Journal 2009, 81, 49–58.

12. Vovk A.I., Kalchenko V.I., Cherenok S.A., Kukhar V.P., Muzychka O.V., Lozynsky M.O. Org. Biomol. Chem. 2004, 2, 3162–3166.
https://doi.org/10.1039/b409526j

13. Cherenok S., Vovk A., Muravyova I., Shivanyuk A., Kukhar V., Lipkowski J., Kalchenko V. Org. Lett. 2006, 8, 549–552.
https://doi.org/10.1021/ol052469a

14. Vovk A.I., Kononets L.A., Tanchuk V.Yu., Cherenok S.O., Drapailo A.B., Kalchenko V.I., Kukhar V.P. Bioorg. Med. Chem. Lett. 2010, 20, 483–487.
https://doi.org/10.1016/j.bmcl.2009.11.126

15. Koren S., Fantus I.G. Best Pract. Res. Clin. Endocrinol. Metab. 2007, 21, 621–640.
https://doi.org/10.1016/j.beem.2007.08.004

16. Trush V.V., Cherenok S.O., Tanchuk V.Yu., Kukhar V.P., Kalchenko V.I., Vovk A.I. Bioorg. Med. Chem. Lett. 2013, 23, 5619–5623.
https://doi.org/10.1016/j.bmcl.2013.08.040

17. Trush V.V., Tanchuk V.Y., Cherenok S.O., Kalchenko V.I., Vovk A.I. Journal of Organic and Pharmaceutical Chemistry 2014, 12, 39–42.
https://doi.org/10.24959/ophcj.14.782

18. Trush V., Cherenok S., Tanchuk V., Kalchenko V., Vovk A. Chem. Biol. Lett. 2015, 2, 1–5.

19. Vovk A., Trush V., Kharchenko S., Tanchuk V., Kalchenko V. Org. Biomol. Chem. 2015, 13, 8803–8806.
https://doi.org/10.1039/C5OB01247C

20. Lugovskoy E.V., Gritsenko P.G., Koshel T.A., Cherenok S.O., Kalchenko V.I., Komisarenko S.V. FEBS J. 2011, 278, 1244–1251.
https://doi.org/10.1111/j.1742-4658.2011.08045.x

21. Kalchenko O.I., Lipkowski J., Kalchenko V.I., Vysotsky M.A., Markovsky L.N. J. Chrom. Sci. 1998, 36, 269–273.
https://doi.org/10.1093/chromsci/36.5.269

22. Chernyshenko V.O., Korolova D.S., Dosenko V.Е., Pashevin D.O., Kalchenko V.I., Pirogova L.V., Chernyshenko T.M., Lugovska O.E., Kravchenko N.А., Makogonenko Y.M., Lugovskoy E.V., Komisarenko S.V. Pharmaceutica Analytica Acta, 2015, 6: 406.
https://doi.org/10.4172/2153-2435.1000406

23. Chernyshenko V.O., Korolova D.S., Nikolaienko T.V., Dosenko V.Е., Pashevin D.O., Kalchenko V.I., Cherenok S.O., Khranovska N.N., Garmanchuk L.V., Lugovskoy E.V., Komisarenko S.V. Biotechnologia Acta 2016, issue 3, 37–43
https://doi.org/10.15407/biotech9.03.037

24. Melezhyk I.O., Rodik R.V., Iavorska N.V., Klymchenko A.S., Mely Y., Shepelevych V.V., Skivka L.M., Kalchenko V.I. Anti-Infective Agents 2015, 13, 87–94.
https://doi.org/10.2174/2211352513666150327002110

25. Ukhatskaya E., Kurkov S.V., Hjálmarsdóttir M.A., Karginov V.A., Matthews S.E., Rodik R.V., Kalchenko V.I., Loftsson T. Int. J. Pharm. 2013, 458, 25–30.
https://doi.org/10.1016/j.ijpharm.2013.10.028

26. Mchedlov-Petrossyan N.O., Vilkova L.N., Vodolazkaya N.A., Yakubovskaya A.G., Rodik R.V., Boyko V.I., Kalchenko V.I. Sensors 2006, 6, 962–977.
https://doi.org/10.3390/s6080962

27. Rodik R.V., Klymchenko A.S., Jain N., Miroshnichenko S.I., Richert L., Kalchenko V.I., Mély Y. Chem. Eur. J. 2011, 17, 5526–5538.
https://doi.org/10.1002/chem.201100154

28. Rodik R.V., Anthony A.-S., Kalchenko V.I., Mély Y., Klymchenko A.S. New J. Chem. 2015, 39, 1654–1664.
https://doi.org/10.1039/C4NJ01395F

29. Shi Y., Schneider H.J. J. Chem. Soc., Perkin Trans. 2 1999, 1797–1803.
https://doi.org/10.1039/a900204i

30. Shulov I., Rodik R.V., Arntz Y., Reisch A., Kalchenko V.I., Klymchenko A.S. Angew. Chem. Int. Ed. 2016, 55, 15884–15888.
https://doi.org/10.1002/anie.201609138

Attachment	Size
mhc171150k.pdf	2.43 MB

Журнал "Макрогетероциклы"

Navigation

Languages

News

Search

References: