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ISSN 1998-9539

The Synthesis and Singlet Oxygen Generation Study of 13(1)-N-Piperazinyl Chlorin e6-15(2),17(3)-dimethyl Ester

Dmitry B. Berezin,a@ Dmitry R. Karimov,b,с Evgeniy A. Venediktov,b Andrey V. Kustov,b,c Vladimir V. Makarov,a,b and Yuliya V. Romanenko

aResearch Institute of Macroheterocycles, Ivanovo State University of Chemistry and Technology, 153000 Ivanovo, Russian Federation
bG.A.Krestov Institute of Solution Chemistry, Russian Academy of Sciences, 153045 Ivanovo, Russian Federation
cIvanovo State Medical Academy, 153000 Ivanovo, Russian Federation
@Corresponding author E-mail:
DOI: 10.6060/mhc151088b
Macroheterocycles 2015 8(4) 384-388
A new monoamide derivative of chlorin e6 containing the piperazine fragment was synthesized and identified with MALDI MS, 1H NMR, UV-Vis and fluorescence spectroscopy. Our photophysical data {lImax(lge) = 665 (4.62); γΔ = 0.52±0.06} indicate that this macrocycle may be considered as a promising sensitizer for photodynamic therapy.
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