Impact Factor 2021 = 1.200 has been issued by ISI Web of Knowledge (JCR 2021).

SCImago Journal & Country Rank

ISSN 1998-9539

Glycodendrimers and Their Derivatives as Potential Therapeutic Agents

I. S. Shchelik,@ A. I. Magasumova, and Yu. L. Sebyakin

Dedicated to Professor Andrej Fedorovich Mironov on the Occasion of his 80th Birthday

M.V. Lomonosov Moscow State University of Fine Chemical Technology, 119571 Moscow, Russia

@Corresponding author E-mail:


DOI: 10.6060/mhc141140s

Macroheterocycles 2015 8(2) 199-217


The carbohydrates are involved in many important biological processes such as cell recognition and cell adhesion. They are presented as a cell surface glycoconjugates, creating a characteristic layer, which surrounds the eukaryotic cell and are called glycocalyx. There is a basic molecular complex of glycocalyx which presents the class of specialized proteins called lectins. To investigate the carbohydrate-protein interactions, synthetic glycosides and glycomimetics as modulators and inhibitors of molecular recognition processes have been used. The present report deals with carbohydrate derivatives, glycolipids and neoglycoconjugates with potential antiadhesion, antiviral, antibacterial, and antitumor activities.



mhc141140s.pdf2.7 MB