The synthesis of N-substituted N,S-macroheterocycles derived from aromatic carboxylic acid hydrazides

Regina R. Khairullina,^@ Bairas F. Akmanov, Tat’yana V. Tyumkina, Regina R. Talipova, Askhat G. Ibragimov, Usein M. Dzhemilev

Institute of Petrochemistry and Catalysis, RussianAcademy of Sciences, 450075, Russian Federation, Ufa, 141 Prospekt Oktyabrya

^@Corresponding author E-mail: ink@anrb.ru, reginessa@mail.ru

DOI: 10.6060/mhc140713k

Macroheterocycles 2015 8(1) 89-93

A selective catalytic cyclothiomethylation method for the synthesis of N,S-macroheterocycles having N-amide substituents is elaborated via the reaction between aromatic carboxylic acid hydrazides, formaldehyde, and α,ω-dithiols possessing from 4 to 6 carbon atoms. Transition metal and rare earth metal salts are used as the catalysts.

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The synthesis of N-substituted N,S-macroheterocycles derived from aromatic carboxylic acid hydrazides

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