Журнал "Макрогетероциклы"

T. K. Rocheva,^a E. V. Buravlev,^a L. I. Mazaletskaya,^b N. I. Sheludchenko,^b D. V. Belykh,^a@ I. Yu.Chukicheva,^a and A. V. Kutchin^a

Dedicated to the Corresponding member of Russian Academy of Sciences Prof. Oscar I. Koifman on the occasion of his 70th Anniversary

^aInstitute of Chemistry, Komi Scientifi c Center, Ural Division, Russian Academy of Sciences, 167982 Syktyvkar, Russia

^bEmanuel Institute of Biochemical Physics of Russian Academy of Sciences; 119334 Moscow, Russia

^@Corresponding author E-mail: belykh-dv@chemi.komisc.ru

DOI: 10.6060/mhc140479b

Macroheterocycles 2014 7(3) 262-266

A number of complexes with transition metal cations (Zn2+, Cu2+, Co2+, Fe3+) were synthesized based on tetra(3,5-diisobornil-4-hydroxyphenyl)porphyrin (1). The antiradical activity estimation of the compounds obtained based on the kinetic characteristics of the reaction with α-phenylethylperoxy radicals showed that the antiradical activity initial porphyrin and its metal complexes is caused by terpenophenolic substituents hydroxyl groups. Among the compounds studied  the free base 1 is of the highest antiradical activity, estimated from the value of the stoichiometric coefficient of inhibition. It decreases in the series Zn-1> Cu-1> Co-1> Fe (OH)-1 for the complexes.

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