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ISSN 1998-9539

Convenient Synthesis of Building-Blocks for Pyridine/Piperidine-Decorated Crown Ethers

Maxim B. Nawrozkij,a Evgeniy B. Gorbunov,b,c Alexandre S. Babushkin,a Evsey A. Ruchko,d Gennadiy L. Rusinov,b,c Valeriy N. Charushin,b,c and Ivan A. Novakova@ 
aVolgograd State Technical University, 400005 Volgograd, Russia
bInstitute of Organic Synthesis of Ural Division of RAS, 620041 Ekaterinburg, Russia 
cDepartment of Organic Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia
dCJSC “PHARM-SINTEZ”, 111024 Moscow, Russia 
@Corresponding author E-mail: 
DOI: 10.6060/mhc140483n
Macroheterocycles 2014 7(1) 18-22


A convenient way to the useful building-blocks for pyridine/piperidine-decorated crown ethers is developed. It is based on NBS-mediated epoxidation, Wagner oxidation and Schwek-Papa reduction reactions, using 2-vinylpyridine as a starting material.



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