Convenient Synthesis of Building-Blocks for Pyridine/Piperidine-Decorated Crown Ethers

Maxim B. Nawrozkij,^a Evgeniy B. Gorbunov,^b,c Alexandre S. Babushkin,^a Evsey A. Ruchko,^d Gennadiy L. Rusinov,^b,c Valeriy N. Charushin,^b,c and Ivan A. Novakov^a@

^aVolgograd State Technical University, 400005 Volgograd, Russia

^bInstitute of Organic Synthesis of Ural Division of RAS, 620041 Ekaterinburg, Russia

^cDepartment of Organic Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia

^dCJSC “PHARM-SINTEZ”, 111024 Moscow, Russia

^@Corresponding author E-mail: president@vstu.ru

DOI: 10.6060/mhc140483n

Macroheterocycles 2014 7(1) 18-22

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A convenient way to the useful building-blocks for pyridine/piperidine-decorated crown ethers is developed. It is based on NBS-mediated epoxidation, Wagner oxidation and Schwek-Papa reduction reactions, using 2-vinylpyridine as a starting material.

References

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Convenient Synthesis of Building-Blocks for Pyridine/Piperidine-Decorated Crown Ethers

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