Improvement of Heterogeneous Sensitizer Photobactericidal Activity by Elongation of Linker between Phthalocyanine and Silica Gel Support

Nina A. Kuznetsova,^a@ Olga A. Yuzhakova,^a Marina G. Strakhovskaya,^b Ludmila K. Slivka,^a Oleg L. Kaliya,^a and Evgeny A. Lukyanets^a

^aOrganic Intermediates and Dyes Institute, 123995 Moscow, Russia

^bDepartment of Biophysics, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia

^@Corresponding author E-mail: lab32@niopik.ru

DOI: 10.6060/mhc131055k

Macroheterocycles 2013 6(4) 363-370

PDF

Aminopropyl groups on the surface of aminopropylated silica gel were lengthened by grafting of additional propylamine units and applied to immobilize singlet oxygen sensitizers of cationic phthalocyanine series. The photobactericidal function of the supported phthalocyanines was markedly increased along with length of spacer.

References

Click here to expand or collapse this section

1. Raab O. Z. Biol. 1900, 39, 524-546.

2. Valduga G., Bertoloni G., Reddi E., Jori G. J. Photochem. Photobiol. B: Biol. 1993, 21, 81-86.
http://dx.doi.org/10.1016/1011-1344(93)80168-9

3. Kuznetsova N. Sensitization of Singlet Oxygen Formation in Aqueous Media. In: Photosensitizers in Medicine, Environment, and Security (Nyokong T., Vefa A., Eds.). Springer Science, 2012. p. 271-318.

4. Kuznetsova N.A., Kaliya O.L., Vorozhtsov G.N. J. Haz. Mater. 2007, 146, 487-491.
http://dx.doi.org/10.1016/j.jhazmat.2007.04.064

5. Patent RF. 1992; N 2036235.

6. Kuznetsova N.A., Yuzhakova O.A., Strakhovskaya M.G., Shumarina A.O., Kozlov A.S., Krasnovsky A.A., Kaliya O.L. J. Porphyrins Phthalocyanines 2011, 15, 718-726.
http://dx.doi.org/10.1142/S1088424611003690

7. Nedachin A.E., Kuznetsova N.A., Dmitrieva R.A., Doskina T.V., Yuzhakova O.A., Kaliya O.L., Maksimkina T.N. Gigena i Sanitariya 2011, N 6, 35-38.

8. Kuznetsova N.A., Yuzhakova O.A., Kozlov A.S., Krasnovskii A.A., Strakhovskaya M.G., Kaliya O.L. Nanotechnologies in Russia 2013, 8, 122-128.
http://dx.doi.org/10.1134/S1995078013010084

9. Kuznetsova N.A., Yuzhakova O.A., Nedachin A.E., Dmitrieva R.A., Doskina T.V., Maksimkina T.N., Kaliya O.L. J. Porphyrins Phthalocyanines 2013, 17, 772-777.
http://dx.doi.org/10.1142/S1088424613500314

10 Zhu J., Sun G. J. Mater. Chem. 2012, 22, 10581-10588.
http://dx.doi.org/10.1039/c2jm16703d

11 Nardello V., Aubry J-M. Tetrahedron Letters 1997, 38, 7361-7364.
http://dx.doi.org/10.1016/S0040-4039(97)10018-1

12 Derkacheva V.M., Lukyanets E.A. Zh. Obshch. Khim. 1980, 50, 2313-2318 (in Russ.).

13 Patent RF. 2010; N 2405785.

14 Kuznetsova N.A., Shevchenko E.N., Makarov D.A., Slivka L.K., Solovyova L.I., Kaliya O.L., Lukyanets E.A. J. Porphyrins Phthalocyanines 2012, 16, 1244-1251.
http://dx.doi.org/10.1142/S1088424612501301

15 Makarov D.A., Yuzhakova O.A., Slivka L.K., Kuznetsova N.A., Negrimovsky V.M., Kaliya O.L., Lukyanets E.A. J. Porphyrins Phthalocyanines 2007, 11, 586-595.
http://dx.doi.org/10.1142/S1088424607000680

16 Krasnovsky A.A., Roumbal Y.V., Strizhakov A.A. Chem. Phys. Lett. 2008, 458, 195-199.
http://dx.doi.org/10.1016/j.cplett.2008.04.091

17 Strakhovskaya M.G., Zarubina A.P., Zhuhovitsky V.G., Mironov A.F., Rubin A.B. Dokl. Biochem. Biophys. 2004, 396, 177-180.
http://dx.doi.org/10.1023/B:DOBI.0000033523.62478.d9

18 Kuznetsova N.A., Gretsova N.S., Derkacheva V.M., Kaliya O.L., Lukyanets E.A. J. Porphyrins Phthalocyanines 2003, 7, 147-154.
http://dx.doi.org/10.1142/S1088424603000203

Attachment	Size
mhc2013_t06n4_363-370.pdf	827.18 KB

Журнал "Макрогетероциклы"

Navigation

Languages

News

Search

Improvement of Heterogeneous Sensitizer Photobactericidal Activity by Elongation of Linker between Phthalocyanine and Silica Gel Support

References