Web of Knowledge определил Импакт фактор журнала Макрогетероциклы за 2021 год: 1.200 (JCR 2021).

SCImago Journal & Country Rank

ISSN 1998-9539

A One Step Synthesis of Boronated meso-Tetraphenylporphyrins

Valentina А. Ol’shevskaya,а@ Аndrei V. Zaitsev,а Yulia V. Dutikova,а,b Valentina N. Luzgina,b Elena G. Kononova,a Pavel V. Petrovsky,a and Valery N. Kalinina


аA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, 119991, Russia

bMoscow State Academy of Fine Chemical Technology, Moscow 117571, Russia


@Corresponding author E-mail: olshevsk@ineos.ac.ru


5,10,15,20-Tetrakis(4-aminophenyl)porphyrin and their metal complexes were used for a one stage synthesis of boronated porphyrins with elevated boron content (~30-35%). The reaction of amino groups in para position of porphyrin phenyl rings with carborane triflates, epoxides and isocyanates smoothly led to carboranylsubstituted secondary amines, amino alcohols and amides potentially applicable in anticancer boron neutron capture therapy (BNCT). 5-(4-Aminophenyl)-10,15,20-triphenylporphyrin was used as a model compound in reactions with above mentioned functionally substituted carboranes.

Прикрепленный файлРазмер
MHC2009_t02n03-04_221-227.pdf533.61 кб